NDGA has been shown to have anti-inflammatory properties, which may improve conditions like arthritis, sciatica, headaches, and stomach pain ( 1). Cellular damage may increase the risk of chronic diseases such as neurodegenerative disease ( 12). This is a process in which molecules called free radicals attack lipids, resulting in cellular damage. Anti-inflammatory activityĬhaparral contains NDGA, an antioxidant that can inhibit lipid peroxidation. The lignans in chaparral are believed to block transcription factor Sp1, which is responsible for replicating virus genes ( 3, 10).Īlthough this is promising, chaparral may cause dangerous side effects, including liver complications, diarrhea, and fever, which are especially dangerous for people with compromised immune systems, including those with HIV ( 11).įurthermore, there is no human research available, making it difficult to know its true effectiveness. There are claims that the chaparral herb can prevent the replication of the human papillomavirus (HPV), human immunodeficiency virus (HIV), and herpes simplex virus (HSV).Ĭhaparral contains many different polyphenols called lignans, which are plant compounds that confer health benefits. However, because of the significant safety concerns of chaparral, including liver failure, no human studies have been conducted ( 5). Other mice and test-tube studies have shown similar antioxidant and anticancer effects associated with NDGA ( 7, 8, 9). In one study, mice treated with a topical application of chaparral-derived NDGA experienced significantly lowered activity of tumor-promoting agents (TPAs), compared with mice who didn’t receive the treatment ( 6). In particular, chaparral leaves and stems contain nordihydroguaiaretic acid (NDGA), a potent antioxidant linked to tumor regression - the shrinkage of tumors ( 3, 4, 5). Anticancer potentialĬhaparral contains various potent compounds that may interact with cancer pathways ( 3, 4). Though research is limited, there are many chaparral-related health claims.
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |